Baldur's Gate 3

It sounds like this won't be a game for hardcore D&D nerds. There's a Q&A with Swen (of Larian Studios) at Pax East where he goes into the details. He says there's no alignment system aspect in character building, since "Wizards of the Coast" asked that they keep that out. However, your characters can align toward good or evil during gameplay, based on the dialogue paths you choose.

Supposedly, the game will be true to the D&D 5th gen rule set. Thankfully though, they designed the gameplay such that the D&D rules operate seamlessly in the background without the player having to worry about it. i.e. Instead of the player calculating & tracking stats, the game itself performs the calcs and displays a simple hit % on screen for the player, etc.

What's most interesting about the gameplay (in single player mode) is that it'll be more like X-Com, where you move every member of your team/party, before the PC takes its turn. During player vs player multiplayer, all players can take their turns simultaneously, speeding up the game sessions and making it more fast paced. Another interesting gameplay mechanic seems to be that thief characters can move between turns, but still risk being detected and countered.